Are you starting a journey with GLP-1 medications like Semaglutide (Wegovy/Ozempic) or Tirzepatide (Zepbound/Mounjaro)? Use this clinical-data-based calculator to estimate your weight loss trajectory over the next year.
Estimated Results
Understanding GLP-1 Weight Loss Expectations
The rise of GLP-1 (glucagon-like peptide-1) receptor agonists has fundamentally changed how we approach chronic weight management. Unlike traditional stimulants, these medications mimic a natural hormone in your body that regulates appetite and blood sugar.
How the Calculator Works
This calculator uses data derived from the STEP (Semaglutide Treatment Effect in People with obesity) and SURMOUNT (Tirzepatide) clinical trials. On average, patients using Semaglutide see a weight reduction of approximately 15% over 68 weeks, while those on Tirzepatide often see reductions exceeding 20% over 72 weeks.
Our algorithm assumes a standard titration schedule—where the dose is gradually increased over the first 4-5 months—meaning weight loss often accelerates after the second month before stabilizing into a steady weekly rate.
Factors That Influence Your Results
- Protein Intake: High protein intake is critical to ensuring that the weight lost comes from fat stores rather than lean muscle mass.
- Resistance Training: Lifting weights or performing bodyweight exercises helps maintain your metabolic rate as you lose weight.
- Starting BMI: Generally, individuals with a higher starting BMI may see faster initial weight loss in terms of absolute pounds.
- Hydration: GLP-1 medications can affect thirst signals; staying hydrated is essential for metabolic function and managing side effects.
The Importance of the "Maintenance Phase"
Weight loss is rarely linear. Most patients experience a "honeymoon phase" in the first 12 weeks, followed by a steady middle phase. Eventually, the body reaches a new set point. The goal of using a GLP-1 weight loss calculator is not just to see how fast the weight comes off, but to prepare for the lifestyle changes necessary to maintain that loss long-term.
Is the Calculator 100% Accurate?
No calculator can predict biology with perfect certainty. Your individual response depends on your genetics, your adherence to the medication schedule, and your metabolic health. Always consult with a healthcare provider before starting any new medication or significant weight loss protocol.